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LUCEMYRA is the only FDA-approved, non-controlled treatment for the relief of multiple symptoms of opioid withdrawal in adults1
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LUCEMYRA is an in-patient or out-patient treatment for patients experiencing:
Opioid Detox
Help patients mitigate withdrawal symptoms when seeking an opioid-free in-patient or out-patient treatment program.
Initiation of Buprenorphine
Prior to the induction of sublingual buprenorphine, ease patients through the 72-hour period of abstinence often needed to avoid precipitating withdrawal.
Transition from Methadone
to Buprenorphine
Help alleviate withdrawal symptoms in patients discontinuing methadone prior to a buprenorphine regimen.
Transition to Extended-Release
Naltrexone
Help mitigate withdrawal symptoms during the 7- to 14-day abstinence period for patients transitioning to extended-release naltrexone injections.
Unplanned Disruptions in Treatment
Help mitigate withdrawal symptoms in patients with unplanned disruption of opioid treatment when opioid-agonists are unavailable or inappropriate for the situation.
After-Treatment Care
Help patients who have completed a successful MAT regimen with buprenorphine or methadone and are set to experience withdrawal symptoms from final step-down off treatment.
Discover how LUCEMYRA helped patients relieve the symptoms of opioid withdrawal
2020 ASAM National Practice Guideline: Recommendations for Treating Opioid Withdrawal2
The American Society of Addiction Medicine (ASAM) recognizes two main strategies for managing opioid withdrawal: gradually tapering the dose of the current opioid(s), or using a non-opioid medication, like LUCEMYRA (lofexidine).
Regarding the use of alpha-2 adrenergic agonists, the Guideline states:
“Lofexidine should therefore be the preferred choice for withdrawal management in an outpatient setting, where monitoring of blood pressure and management of hypotension is more difficult.”
-American Society of Addiction Medicine, 2020
Learn more about the 2020 ASAM Guidelines
